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Self-organizing systems consist of components whose local interactions produce global behaviors such as spontaneous self-assembly, motion, computation and replication.
In our lab we engineer self-organizing systems that have predictable, robust behaviors. We work with a variety
of substrates: We build distributed robot systems that use stochasticity to their benefit; we build synthetic in vitro
biochemical networks, made from bits of DNA, RNA and a few enzymes, that implement desired I/O specifications;
We build new genetic regulatory networks for bacteria or yeast; We design evolutionary systems in which bacteria
optimize their metabolisms for our benefit.
We are particularly interested in dynamical systems, feedback control, stochastic processes and concurrency applied to self-organization.
The ultimate goal is to engineer self-organizing systems at the molecular level. Some the the long-term
applications of our work include gene therapy, tissue engineering, and biosensing.
- -Eric Klavins
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Past news items . . .
- UW's iGEM team goes to Cambridge and brings back a bronze medal. Congratulations! (11/2008)
- Caltech and UW are awarded $10M from the National Science Foundation for the Molecular Programming Project! Read the press release or visit the MPP website. (9/2008)
- J. M. McNew successfully defends his thesis on Nondeterministic Modeling and Verification of Networked Robotics Systems to become the SOSLab's first graduated Ph.D. Congratulations J.M.! (8/2008)
- SOSLab postdoc David Thorsley awarded best presentation in session for both of his American Control Conference papers presented June 11, 2008 in Seattle, WA. Congratulations David!
- SOSLab awarded an "A. Richard Newton Breakthrough Research Award" from Microsoft to study stochastic processes inside single cells of genetically engineered bacteria. See David Thorsley's ACC 2008 Paper for the main idea. See also this obituary of A. Richard Newton, in whose honor these awards were given. (3/2008)
- The Center for Molecular Cybernetics, an NSF Chemical Bonding Center dedicated to the study of single-molecule robots, launches its new web site (12/2007).
- SOSLab PI Eric Klavins is co-PI in a new $2M NSF grant: EFRI-ARESCI: Controlling the Autonomously Reconfiguring Factory with MIT, Cornell and U. Penn. (8/2007)
- Sam Burden has been awarded with a UW Research Fellowship for Advanced Undergraduates. Congratulations Sam! (8/2007)
- The programmable parts appear on the cover of the August issue of Control Systems Magazine! (7/2007)
- SOSLab graduate student Fay Shaw passes the ME qualifying exam. Congratulations Fay! (5/2007)
- 3/2007: SOSLab graduate student J.M. McNew passes the EE general exam. Congratulations J.M.!
- 3/2007: We are gradually moving all online content to a new wiki. Check it out. The BioCircuits course is the first big section.
- 1/2007: We are developing a new course for Spring 2007: An Introduction to BioCircuits! Sign up!
- 10/2006: Josh Bishop (with Fay Shaw and Eric Klavins) wins Best Poster in the UW Center for Nanotechnology's Poster Competition. The title: "Improved Repeatability of a DNA Nanomotor".
- 9/2006: The latest videos of the programmable parts have been posted.
- 4/2006: SOSLab gets visitors as part of the COE open house.
- 2/2006: Chandy (Caltech), Doyle (Caltech), Klavins (UW), Murray (Caltech, PI) and Parillo (MIT) receive MURI Award for their proposal: "High Confidence Design for Distributed Embedded Systems".
- 2/2006: Eric goes to physical biology bootcamp at the Rob Phillips Lab.
- 12/2005: SOSLab Undergrad Sam Burden wins Mary Gates Fellowship -- again.
- 11/2005: SOSLab Graduate Students Josh Bishop and Nils Napp pass their qualifying exams! Congratulations!
- 9/2005: SOSLab's programmable parts are featured at the NSF's Exhibition of U.S. Robotics Research.
- 6/2005: SOSLab's 16-processor cluster is up and running (check usage) -- thanks to Richard Kreisberg.
- 4/2005: SOSLab opens its doors to local K-12 students as part of UW Engineering's Open House. (See photos.)
- 2/2005: SOSLab's "programmable parts" are self-assembling! (Read more.)
- 1/2005: New grant: "DNA Machines" funded by UW's Royalty Research Fund.
- 12/2004: SOSLab Undergrad Sam Burden wins Mary Gates Fellowship.
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- N. Napp, S. Burden and E. Klavins. Setpoint Regulation for Stochastically Interacting Robots, Robotics: Science and Systems V. MIT Press. 2009.
- D. Thorsley and E. Klavins. A Theory of Approximation for Stochastic Biochemical Networks, Control-Theoretic Approaches in Systems Biology. Eds. B. Ingalls and P. Iglesias. MIT Press, 2009. preprint
- J. Bishop and E. Klavins. An Improved Autonomous DNA Nanomotor. Nanoletters, Sep., 2007. Vol. 7, No. 9, pp. 2574-7. pdf
- Full publication list
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